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科学研究
RESEARCH
A Semiparametric Additive Rates Model for the Weighted Composite Endpoint of Recurrent and Terminal Events
时间  Datetime
2020-10-21 14:00 — 15:00
地点  Venue
Zoom APP(2)()
报告人  Speaker
孙六全
单位  Affiliation
中国科学院数学与系统科学研究院
邀请人  Host
刘卫东
备注  remarks
zoom会议号: 662 319 22112 会议密码: 506294
报告摘要  Abstract

Recurrent event data with a terminal event commonly arise in longitudinal follow-up studies.

We use a weighted composite endpoint of all recurrent and terminal events to assess the overall effects of covariates on the two types of events. A semiparametric additive rates model is proposed to analyze the weighted composite event process and the dependence structure among recurrent and terminal events is left unspecified. An estimating equation approach is developed for inference, and the asymptotic properties of the resulting estimators are established. The finite-sample behavior of the proposed estimators is evaluated through simulation studies, and an application to a bladder cancer study is illustrated.